http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-192955-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-19 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
filingDate | 1983-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_467c40b53dbcf38be417c301e6415da7 |
publicationDate | 1987-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | HU-192955-B |
titleOfInvention | Process for producing a-21978 ccyclic peptide derivatives acilyzed with alkoxy-benzoyl-group |
abstract | A process for the preparation of A-21978C cyclopeptide derivatives having the formula I resulting from the formula sheet, wherein R is a benzoyl group -OR 2 and X-substituted, in which R is high C 2 C 8-C 15-alkyl and X is Hydrogen, chlorine, bromine, iodine, nitro, C deep 1-C deep 3-alkyl, hydroxy, C deep 1-C deep 3-alkoxy or C deep 1-C deep 3-alkylthio and in which R is high 1 for hydrogen or an amino protecting group, or pharmaceutically acceptable salts thereof, by reacting a corresponding nucleus of A-21978C of Formula I wherein R is hydrogen to give a free amino group and the other two free amino groups either unprotected or optionally protected by a protecting group or a corresponding pharmaceutically acceptable salt thereof with an acylating agent which is the free benzoic acid derivative corresponding to the substituted benzoyl group R or a benzoyl group activated ester thereof. A preferred compound hereafter available is N-deep Trp-p- (n-dodecyloxy) benzoyl-A-21978C. |
priorityDate | 1982-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.