abstract |
New octahydro-indolo(2,3-a) quinolizine deriv. (I) was prepd. by reaction of hexahydroindolo-(2,3-a) quinolizine salt (II) with an alkaline and then with a paraformaldehyde. The obtd. salt is dissolved in an alkanol, filtered and the filtrate is treated with acid after chromatographic analysis. The racemic or optically active prod., where R is 1-6 C atom alkyl gp., is used as antidepressant. |