http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-191842-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5e07888f923b7443f3b8eb913614893 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-42 |
| filingDate | 1983-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c6c7ce5718cc957871c0e1cf911293d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e90d3635d1850b723f97b924c758ff79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01d2d619508f681eba635cd26b3ae14b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e27f546fb55cd509f633703376099d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5938f7bdefeb5a963b1101bcdc54554c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b83a04a102b1ee35648f439b14f936f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbf01ea97dfaea0794948c0d13897f13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8722201621a6cb93e41fe2c4bd6fea5 |
| publicationDate | 1987-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-191842-B |
| titleOfInvention | Economical industrial process for the production of high purity d-/-/-penicillamine |
| abstract | High purity D-(-)penicillamine is prepd. by reacting naturally occurring penicillin salts e.g. benzyl- or phenoxy-methyl-penicillin, or penicillin acids e.g. phenoxy-methyl-penicillin with hydrazinium-hydrochloride, acetic-acid and hydrochloric-acid at 20-120 deg.C for 1-30 hrs. with constant stirring in an inert solvent with b.pt. below 120 deg.C contg. no or less than 20wt.% water and removing the water from the reaction mixt. during or at the end of the reaction by azeotropic distillation. - The reaction prod. is sepd. from the reaction mixt. by filtration, washed with aliphatic alcohol, mixed with ethanol and treated with hydrochloric-acid and filtered. The filtrate is purified with charcoal and treated in a nitrogen atmosphere in the presence of an equiv. amt. acetic-acid with a base, pref. diethyl-amine. The resulting crystalline prod. is filtered, washed with aliphatic alcohol and dried. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108164444-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108164444-B |
| priorityDate | 1983-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.