http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-191459-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f88f84fc279fe5d0b9b5ec3c88c2e2b2 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C325-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C335-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23D9-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L27-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C313-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-44 |
| filingDate | 1982-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5989e4f1738b7c1f78608c38a353d9d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab8125b2922b266ab9a2d2d7e71b72d5 |
| publicationDate | 1987-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-191459-B |
| titleOfInvention | Process for preparing n-/aryl-thio-alkyl/-n'-/amino-alkyl/-carbamide derivatives and pharmaceutical compositions containing thereof |
| abstract | The present invention relates to a process for the preparation of the N- (arylthioalkyl) -N '- (aminoalkyl) urea of the formula (I) and its thiourea derivatives and their sulfinyl and sulfonyl analogues, acid addition salts and laxates thereof. , Ar1-B1-N-C-N-alk2-N (I) R4 is phenyl substituted with Ar 1 or 2-naphthyl, order or 1-3, wherein the substituents are identical or may be different and have 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms or halogen, and Ar may include a group-linked intermediate methylene group, R 1 and R 2 hydrogen, C 1-5 alkyl or phenyl-C 1-4 means alkyl, X represents oxygen or sulfur, II represents thio, sulfinyl or sulfimyl, R3 and R4 have the same or different meanings and C1-4 alkyl or phenyl-C1-4 alkyl group; or R 3 and R 4 are piperidinyl or C 1-4 alkyl-piperazinyl at the adjacent nitrogen atom and alk 1 and C 2 are C 1-7 -alkylene or C 1-4 -alkylene-C 1-4 -alkyl and may have the same or different meanings . The compounds exhibit antiarrhythmic activity. -1- |
| priorityDate | 1981-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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