http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-187351-B

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filingDate 1981-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1985-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber HU-187351-B
titleOfInvention Process for producing pyrazolidine-dion derivatives
abstract The present invention relates to a novel process for the preparation of 1,2-diphenyl-4- [2 (phenylthio) -ethyl] -3,5-pyrazolidinedione in the presence of malonic acid dialkyl ester and 1,1'-dihalethane in the presence of an alkali metal alkanolate and the resulting \ t reacting cyclopropane-1,1-dicarboxylic acid dialkyl ester with thiophenol and then reacting the resulting 2- [2 (phenylthio) ethyl] malonic acid dialkyl ester with 1,2-diphenylhydrazine such that the malonic acid dialkyl ester and 1 The 3-component ester mixture obtained by reacting 2-dihaloethane in the presence of an alkali metal alcoholate is reacted with thiophenol and the resulting 2- [2- (phenylthio) ethyl] malonic acid dialkyl ester, malonic acid dialkyl ester, and butane-l, 4.4 distillation of the malonic acid dialkyl ester from a mixture of tetracarboxylic tetraalkyl esters, and selectively reacting the remaining two-component mixture with 1,2-diphenylhydroxy in the presence of alkanol, preferably butanol. recovered. The compound of the present invention is a production intermediate of sulfinpyrazone. -1-
priorityDate 1981-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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