http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-186989-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d709e3167fa2f99a1803c9cfeb0aca63 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D457-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D457-02 |
| filingDate | 1982-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d185ce0dd1447b88cb0c6d804d723313 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4a51eb3bc117d27694290a0ccde26b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe6ad5bf92a9e8a04d2fee8de3a9fb56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_227c481152820d3747330893418cf6b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e144fdccc9be3e161c7489e226d3cd9 |
| publicationDate | 1985-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-186989-B |
| titleOfInvention | Process for preparing new ergoline derivatives |
| abstract | FIELD OF THE INVENTION The present invention relates to novel ergoline derivatives of formula (I): wherein R 1 is hydrogen or methyl, R 2 is hydrogen, halo, methyl, R 1 is hydrogen or methoxy, R 1 is C 1-4 alkyl or 3 to 4; C5 alkenyl, Xj is oxygen, sulfur or imino, A is carbonyl or sulfonyl, B is C1-4 alkyl, phenyl optionally substituted with C1-4, optionally substituted halogen, pyridyl, n 0, 1 or 2, and pharmaceutically acceptable salts thereof. According to the present invention, an ergolamine of formula (II) wherein R *, R 2, R 3, R * and n are as defined in the organic solvent, is an isocyanate, isothiocyanate or isoiminocyanate of formula (III): B is a reaction as defined above. The compounds of the invention have antihypertensive activity and are effective for the gastrointestinal tract. X »C« N-A-B -1- |
| priorityDate | 1981-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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