| abstract |
Pharmacologically active thiazolo[3,2-a]pyrimidines of the formula <IMAGE> wherein A is a bond between the alpha - and beta -carbon atoms or (-CH2-) group; R1 and R2 represent hydrogen, C1-C4 alkyl, cyano, CF3, thienyl, pyridyl, biphenyl, naphtyl, phenyl optionally substituted, <IMAGE> wherein R' and R'' are hydrogen or alkyl; R3 represents hydrogen, halogen, alkyl, OH, formyloxy, alkanoyloxy, alkenyloxy; R4 represents substituted pyrrole, substituted phenyl or substituted thiazolyl. The compounds have antiinflammatory, antiulcerorgenic and antigastric secretory activity. |