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filingDate 1982-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aba3f130ffbc5f3891bfd8cdfdd1d487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6af879323ee27c83a997bce07c7bc204
publicationDate 1985-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber HU-186845-B
titleOfInvention Process for producing new erythromycin compounds and pharmaceutical compositions containing them as active agents
abstract There are prepared new erythromycin A compounds of the general formula in which R is deep 1 for methyl, while R is low 2, R deep 3, R deep 4 and R deep 5, which may be identical or different, for hydrogen atoms or C deep 1-C 3-alkanoyl groups or R 4 and R 5 together can form a C = O group and a new process for their preparation, which comprises: a) 11-aza-10-deoxo-10-dihydro-erythromycin A the above formula (1), in which R deep 1, R deep 2, R deep 3, R deep 4 and R deep 5 are identical and represent hydrogen atoms, is reacted with formaldehyde, b) the product of the formula (1) obtained, in which R deep 1 for methyl and R deep 2, R deep 3, R deep 4 and R deep 5 represent hydrogen atoms, reacted with Aethylenkarbonat, and c) the products according to the above steps a) and b) of the acylation with Carbonsaeureanhydriden the formula 2 R deep 6-OR deep 7, in which R deep 6 and R deep 7 the meanings for R ti ef 2 or R deep 3 o. R deep 4 and R deep 5, respectively, provided that they stand for C deep 1-C deep 3Alkonylgruppen subjects, provided provided. The new compounds have an antibacterial effect.
priorityDate 1981-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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