| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f68254c2256a29224bb518f200d45ce9 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-087
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-087
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-08 |
| filingDate |
1982-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08e4e7a69f585a5f665ddd9d124c81e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24d3d7b4f6b54cd8208e0b9a41cc876f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f31a185e729d9412b4a235c061e206f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b436b1a9ef2b59b64a6e5c5a6c21fb70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ecdb4b03df7acb6d64eb4617feeb769
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f5ca36c03d1c8f93ddf5eae15cceec8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2040395a653d3139e3e0419987978fa |
| publicationDate |
1985-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
HU-186566-B |
| titleOfInvention |
Process for immobilisation of combinations consisting nucleofil group |
| abstract |
The invention relates to a process for the immobilization of compounds comprising nucleophilic groups. According to the process of the invention a polymer comprising an amido group is swollen in a buffer. For this purpose any buffer is suitable which contains no amino, sulfhydryl and/or hydroxy groups in the molecule. To the swollen polymer a solution of a quinone - preferably p-benzoquinone - in a water miscible organic solvent is added and the mixture is activated at 273 DEG -343 DEG K. for 0.5-48 hours - preferably for 24 hours. The unreacted quinone is washed out with an aqueous solution of a water miscible organic solvent and thereafter water and/or a buffer. To the purified gel at a pH value between 3 and 11 - preferably between 6 and 8 - a buffered solution of a compound comprising a nucleophilic group is added, the suspension is incubated at 260 DEG -313 DEG K. for 24 hours, the gel is separated and the non-bound compound comprising a nucleophilic group is removed by washing. |
| priorityDate |
1982-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |