http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-185960-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b125e90a7a4dac6558467de77518d6b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-38 |
| filingDate | 1981-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6228562f9a1c579589d61ad893fae12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f330c920737fd54023e55168b8e3bbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c59e811877f6a677950f87d6935afa3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe38fcb039d0eb12d5512203aa7d1a27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cce82b5cc870e8870b1071d8995b4be4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3b0950fff58beba3ec14528e52c494c |
| publicationDate | 1985-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-185960-B |
| titleOfInvention | Process for producing optically active alpha-aminophosphonic acids and optically active n-acyl-alpha-aminophosphonic acids |
| abstract | The present invention relates to optically active α-aminophosphonic acids of formula (I) and optically active N-acyl-α-aminophosphonic acids, wherein R 1 is C 1 -C 6 straight chain alkyl optionally substituted with phenyl or phenyl. ; R2 is C1-C4 alkyl optionally substituted by halogen. According to the method, a racemic N-acyl-α-aminophosphonic acid of formula (II) is resolved in an aqueous medium at pH 6-8 with an aminoacylase enzyme, and the deacylated La-aminophosphonic acid enantiomer is separated into the unaltered DN-eye. foszfonsavtól. This compound is desacylated if desired. If necessary, L-α-aminophosphonic acid is converted to L-Nacyl-α-aminophosphonic acid by acid chloride or acid anhydride. As an appropriate solution, the aminoacylase is used in an immobilized form. The advantage of the process is that the resolving agent is a non-costly, stable formulation with high yield, high-purity end-product. I II / OH R, -C-P I • OH NH 2 H 0 'I / OH NH OH o = c-r 2 (ii) -1- |
| priorityDate | 1981-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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