| abstract |
New phenylalkylamines of the general formula I where R 1 is a hydroxy group or an optionally substituted amino group, R 2 is low and R 3 is halogen atoms, trifluoromethyl, cyano or nitro groups or one of the radicals R 2 or R 3 is also a hydrogen atom R 4 is a hydrogen atom or an alkyl group, R 5 is a hydrogen atom, an alkyl, cycloalkyl, alkenyl or aralkyl group, A is the methylene, ethylene or hydroxymethylene group and B is an optionally substituted aralkyl group, which is linked to the phenyl nucleus Methylene group may be replaced by an oxygen or sulfur atom, a sulfinyl or sulfonyl group, their optically active antipodes, their diastereomeric racemates and their optical antipodes, and their Saede addition salts, which have valuable pharmacological properties, in particular an effect on the heart and circulation. The compounds of the formula I can be prepared by conventional methods for analogous compounds. |