http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-185307-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 1981-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42dc5d3b4e1a7bfed1385fe248b463af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16688af6909dfce86a9b1c3b7d7158a6 |
| publicationDate | 1985-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-185307-B |
| titleOfInvention | Process for preparing vincaleucoblastine derivatives |
| abstract | Dimeric indole-dihydroindole compounds of the formula I …<CHEM>… wherein… R is OCH3, NH2, NHCH3, NHC2H5, NHC2H4OH or NH-NH2;… R<1> is OH or acetoxy;… R<2> is CH3 or CHO; and… R<4> is ……NH-@-R<5> wherein R<5> is H, methyl, …<??>NHCOO methyl or methylthiomethyl; and their pharmaceutically-acceptable acid addition salts, active as anti-tumor agents in mammals, are prepared from their C-4 min hydroxy analogues by reaction with hydrogen cyanide or nitriles under strongly acidic conditions. |
| priorityDate | 1980-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.