http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-183579-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c91bbf0395db010b4806f50d808c4e |
| filingDate | 1981-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a207a665fee541ceddbda684becc4a3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d288dcfc66bd0b5da3830ac231832f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c028ee521b90b04c109b0f3f202ea0d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25a26c8f31a5f291234207a082f791c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea6ada2ba4eb9b5f730cafd2af74b488 |
| publicationDate | 1984-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-183579-B |
| titleOfInvention | Process for producing l-arginyl-l-lizyl-l-asparagyl-l-valyl-l-tirosine pentapeptide |
| abstract | The present invention relates to a novel process for the preparation of L-arginyl-L-lysyl-L-aspartyl-L-valyl-L-tyrosine pentapeptide (TP-5) by stepwise chain extension in solution, in which the L-valine, L, in each coupling step is used. as the amino-terminal protecting group for aspartic acid and L-lysine, a benzyloxycarbonyl group, a t-butyloxy group for the protection of the L-aspartic acid / 1-carboxyl group, an ω-amino group of the L-lysine, and an amino-terminal protecting group for the last coupling step in L-arginine. and the tert-butyloxycarbonyl group is used and the amino-terminal protecting group is removed by catalytic hydrogenation, with the exception of the last step, after each coupling step, and after the final coupling step, all the protecting groups present are removed by treatment with trifluoroacetic acid. In this way, a very pure product is obtained without any harmful reaction. -1- |
| priorityDate | 1981-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.