abstract |
The invention relates to a plurality of preparation processes of compounds of the formula I, in which an adjacent pair of R 5, R 6, R 7 and R! and R & ind8! a string -CZC (G & ind1!) = (& ind2) -Z-forms, R & ind4 !, R & ind9! and the rest of R & ind5 !, R & ind6 !, R & ind7! and R & ind8 !, which may be the same or different, are each hydrogen, alkyl, halogen, alkenyl, -NO & ind2 !, - NR & ind! R & ind2 !, -OR & ind3 !, -S (O) & n! R & ind3! or alkyl substituted by hydroxy, amino, alkoxy or carbonyl oxygen, N-0.1 or 2, R & ind1! and R & ind2 !, which may be the same, are each hydrogen, alkyl, -CONHR & ind3 !, phenyl or phenyl substituted by alkyl or halogen, or R & ind1! and R & ind2! together with the nitrogen atom to which they are attached form a 5- or 6-membered heterocyclic ring, R & ind3! Is hydrogen, alkyl, alkenyl or phenyl, one or two of the atoms a, b, c, and d are nitrogen atoms and the rest are carbon atoms, where R & ind9! has no significance if two of the atoms a, b, c and d are nitrogen (with certain exceptions) as well as their pharmaceutically acceptable derivatives. The new compounds have an antiallergic effect in the broadest sense. |