http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-182818-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c91bbf0395db010b4806f50d808c4e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D461-00 |
| filingDate | 1978-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f27161fc949293bd9ec7ee2536305ec8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52c201fd4a2314a529451b07a5ee3826 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47ce47223b27bfb76b237dc27cb6e14c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cb3729b65365bcb045a0eea5415c2ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71852dbd12d8e0d35992e7aa0aa1adac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9bd313d852a9f2625cfac050363f2bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41e04ade255a6d664a98b2011345b48f |
| publicationDate | 1984-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-182818-B |
| titleOfInvention | Process for preparing new oxyamino-eburnan deriavtives |
| abstract | The present invention relates to a 14-epimer mixture of novel oxyaminobumane derivatives of the formula V wherein R1 and R2 are C1-C4 alkyl, and R3 is halogen-substituted phenyl: C1- (C1-C4) alkyl - or an acid addition salt thereof, by the addition of an oxyamino-E-homoburnan derivative of formula IV wherein R2 and R3 are as defined above, by addition of an alkali metal to an alcohol of formula R1-OH wherein R1 is as defined above. and, if desired, converting the resulting oxyaminoburnan 14-epimer mixture of formula V to an acid addition salt. The oxyaminobumane compounds of formula V are novel. They are important because they may be the starting material for the pharmacologically significant apovinkamic acid ester derivatives having vasodilatory activity. IV 0-R3 V -1- |
| priorityDate | 1978-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.