http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-181054-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_21a39b3e9cbd64f50e4548ff455b6e89 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-16 |
| filingDate | 1980-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c5c18544a250b94fb00be235fc7dfbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a432a11948d3b2cc739b124edc91e24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b862f24c29e5fb343be6ee19c0e06d14 |
| publicationDate | 1983-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-181054-B |
| titleOfInvention | Process for producing triptamine derivatives |
| abstract | A tryptamine compound of formula (I): <IMAGE> in which R = hydrogen, halogen, C1-6 alkyl, aryl, aralkyl or nitro; R<2> = hydrogen, C1-6 alkyl, C1-6 hydroxyalkyl, aryl or aralkyl; R<1> and R<3> are each the same component as that which is defined for R<2> or R<4>-CO-, where R<4> = C1-6 alkyl, aryl or aralkyl; R<1>, R<2> and R<3> may be identical to each other or be different from each other; the group <IMAGE> may be <IMAGE>, where n = 1-3, m = 2 or 3 and X = -CH2-, -O-, -N- or -S-, and, if R<2> = alkyl, R<3> = R<4>-CO-, R<4> = alkyl and if the sum of the number of carbon atoms of the alkyls represented by R<2> and R<4> = 4 to 8, the group <IMAGE> may be of formula <IMAGE> in which l = 4-8, is prepared by reacting a phenylhydrazine compound of formula (II): <IMAGE> with a 4-aminobutanal dialkyl acetal compound comprising at least one group of formula (III): <IMAGE> in a medium comprising at least one component chosen from water and hydrophilic organic solvents, the pH of the mixture being maintained at a value from 0.8 to 4. The tryptamine compounds have a pharmacological activity, especially a vasopressor activity. The process is simple and gives a high yield. |
| priorityDate | 1979-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 177.