http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-180002-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28a869d6fc950d50f6df03f549ca3afa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 |
| filingDate | 1979-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b4333993a74dbbd4defc2b4456b908c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_453a3693a69a54a22f024a82d7194e95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ebb53dd03cf8c81959fe954d1280dc6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6937bedd2c4f2a016cc45827932a87b0 |
| publicationDate | 1983-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-180002-B |
| titleOfInvention | Process for producing new 4-figure bracket-p-square bracket-bis-bracket-2-chloro-ethyl-bracket closed-amino-square bracket closed-phenyl-figure bracket closed-buty ic acid derivatives for estradiol |
| abstract | NEW MATERIAL:An addition compound II composed of an esteradiol derivative and chlorambucil. USE:Anti-tumor agent, having selectivity to cancer cells having receptors, and low side effects. Especially effective to breast cancer, solenoma, prostatic cancer, nephritic cancer, thyroid cancer, etc. PROCESS:The objective compound X is prepared by reacting the 17-OH group of estradiol with a functional group-introducing agent (e.g. monobromoacetyl bromide) in a solvent such as THF, etc., and then reacting the reaction product with an anti- tumor agent (e.g. silver salt of chlorambucil) in a solvent such as DMSO at 0- 100 deg.C for 2-74 hours. |
| priorityDate | 1978-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.