| abstract |
D-homosteroids of the formula <IMAGE> WHEREIN R3 alpha is hydrogen, R3 beta is hydroxy, lower alkanoyloxy or aroyloxy and R3 alpha and R3 beta taken together are oxo; R17a alpha is hydrogen, lower alkyl, ethynyl, vinyl, allyl, methallyl, propadienyl, 1-propynyl, butadiynyl or chloroethynyl; R17a beta is hydrogen, alkanoyl, aroyl, lower alkyl, cycloalkyl-lower-alkyl, benzyl, furfuryl or tetrahydropyranyl; R18 is hydrogen or methyl and the dotted line in the C-ring denotes an additional carbon to carbon bond in the 11,12-position and PROCESSES FOR THE PREPARATION THEREOF ARE DISCLOSED. |