http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-177271-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c902faf6ae746c51fc8010672fc22894 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-224 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-234 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-224 |
| filingDate | 1976-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b502a5bea5aa4ae43c9fc4240833a5f9 |
| publicationDate | 1981-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-177271-B |
| titleOfInvention | Process for preparing neamine-6-0- and -3-0-d-glycosyl analogues |
| abstract | 1530643 Aminoglycosides UPJOHN CO 19 Aug 1976 [8 Sept 1975] 34527/76 Heading C2C Novel aminoglycosides of the general formula wherein T is hydrogen or an amino blocking group; Q is T as defined above or a group of the formula in which n is one, 2 or 3; either W and X are both H or optionally substituted hydrocarboncarboxylic acid acyl radicals of from 2 to 18 carbon atoms and any substituent is selected from halogen, nitro, hydroxy, amino, cyano, thiocyanato and alkoxy or W is hydrogen and X is a glycosyl group selected from pentafuran. osyl, hexapyranosyl and aminopyranosyl of the formula wherein R 1 is hydroxy, acetyloxy, benzoyloxy, benzyloxy, amino, acylamino of from one to 8 carbon atoms, alkylamino of from one to 5 carbon atoms or N-alkylacylamino in which the acyl group is of one to 8 carbon atoms and the alkyl group is of one to 5 carbon atoms and R 2 is hydrogen or acetyl, with the provisos that R 1 is not amino at the 3<SP>11</SP> or 3<SP>11</SP> and 6<SP>11</SP> positions when R 1 at the other positions is hydroxy and that Y is not D-glycosyl; either Y is hydrogen or glycosyl as defined above and Z is hydrogen or Y and Z are taken together and are -CL 1 L 2 - (L 1 and L 2 are alkyl and the total number of C atoms in CL 1 L 2 is not more than 8) with the overall provisos (1) that when W and X are both optionally substituted hydrocarbon-carboxylic acid acyl radicals and Q is then Y is glycosyl and Z is hydrogen; (2) that X and Y are not both glycosyl; (3) that T is not hydrogen when Y and Z are -CL 1 L 2 - or W, and X are both optionally substituted hydrocarbon-carboxylic acyl radicals and Y and Z are both hydrogen; and (4) that when T is H then W and X are both H and non- toxic pharmaceutically acceptable acid addition salts thereof are prepared by removing protecting groups and, if present, acyl groups from a corresponding N-protected and optionally O-acylated compound. They have antibacterial activity and can be included in pharmaceutical compositions. |
| priorityDate | 1975-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 189.