| abstract |
2,9 alpha -Dichloro-6 alpha -fluoro-16 alpha -methyl-11 beta ,17,21-trihydroxy- pregna-1,4-diene-3,20-dione compounds of the formula (I) <IMAGE> (R1, R2 = OR where R = H, acid residue) have antiinflammatory effects. They are prepared by reacting corresponding 2-dechloro compounds with chlorine and subsequently eliminating HCl from the 1,2-dichloro compounds obtained in this way. |