http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-176558-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb3edb9a697ebfa78026d99c5a81b3c3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0088 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 |
| filingDate | 1977-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a67809bf6ddacde48df2b7c138e6d9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ce6b22ed58b2107e4a7c3a91e55c6ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a2b13911ae948a2b86664c49a6b5f52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23a28427176531c981de384a69d70f0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_296e29ed4a1c506fb44f140cfd677943 |
| publicationDate | 1981-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-176558-B |
| titleOfInvention | Process for preparing new n-enolesters of steroids |
| abstract | 1527161 Steroid 3-enol esters LEO AB 18 Feb 1977 [19 Feb 1976] 06512/76 Heading C2U The invention comprises compounds of formula wherein St is a steroid #<SP>2</SP>-3-yl or #<SP>3</SP>-3-yl radical comprising up to 40 carbon atoms (inclusive of substituents) and a total of 1-4 double bonds in the gonane nucleus; and R is wherein R<SP>1</SP> is C 2-4 #- or γ-haloalkyl (the halogen being Cl or Br); R<SP>2</SP> is H, C 1-4 alkyl, C 1-4 alkoxy or halo; A is a C 1-4 n-alkylene or C 2-4 n-alkenylene radical optionally bearing (a) 1 or 2 C 1-4 alkyl groups, and/or (b) an amino or C 1-4 alkanoylamino group on the carbon atom adjacent to the CO; X is O or S; and k and m are each 0 or 1, k being 1 when m is 1. Preparation of I is by enol esterification of the parent storoid 3-ones. Modifications and alternative preparations are also described but not exemplified. Anti-tumour compositions for oral, parenteral, topical, rectal and vaginal administration comprise a compound I and a carrier. |
| priorityDate | 1976-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 145.