http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-176008-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be3928f66bb2545a8175c61c56146b9a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J21-00 |
| filingDate | 1974-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4790f2ca4d3c400af36642df8b02645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_921aff14279d6a84fdc2b9b2dec4af69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03633850a0e2fc172ee5c3a9651f5666 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db207000d4b0aac5d806792b360d8772 |
| publicationDate | 1980-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-176008-B |
| titleOfInvention | Process for preparing tropane derivatives |
| abstract | 1459908 Tropane alkaloid intermediates SANWA KAGAKU KENKYUSHO CO Ltd 12 Aug 1974 [15 Oct 1973] 35510/74 Heading C2C A process for the preparation of an N-aeyldehydronortropinone of the formula wherein R is alkyl, aryl, alkoxy or hydrogen; and R<SP>1</SP> and R<SP>11</SP> are alkyl, hydrogen or halogen, comprises reacting an N-acylpyrrole of the formula with an α,α<SP>1</SP>-halogenoketone of the formula wherein X is halogen, in the presence of a reducing agent, e.g. iron carbonyl or a zinccopper couple. The products may then be subjected to a stereo-selective reduction wherein either the double bond between the 6- and 7- positions is reduced, e.g. by catalytic hydrogenation, and/or the N-acyl and 3-oxo groups are reduced by, for example, LiAlH 4 , to give a tropine or dehydrotropine of the formula or a 2,4-dialkyl derivative thereof, via a compound of the formula |
| priorityDate | 1973-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.