| abstract |
The present invention relates to compounds of the formula wherein A is -R 1, - (CR 3 R 4) n -R 1, - (CR 3 R 4) m R 5 (CR 6 R 7) p -R 1 and - (CR 3 R 4) n (CR 6 R 7) p -R 1; Q is -R2, - (CR3R4) n-R2, -R5 (CR3R4) p-R2, (CR11R12) mR5 (CR6R7) p-CR2, (CR11R12) n (CR6R7) p-R2, -S (O) R2 a group wherein R 2 is other than hydrogen and a group of the general formula -S (O 2) R 2 wherein R 2 is other than hydrogen; X-Z, - (CR 3 R 4) n -Z, -CH = CH 2 and - (cycloalkyl) -Z, and their pharmaceutically acceptable salts, prodrug esters and co-stereoisomers, as well as their use and pharmaceutical compositions containing them. The compounds are useful for the treatment of diabetes, in particular type II diabetes. |