abstract |
The present invention relates to compounds of the general formula wherein G is optionally substituted with aryl or heteroaryl; Z is oxygen; E is a sulfonyl group or an optionally substituted methylene group or a nitrogen atom; M is methyl; A1 and A2 are CR7- wherein R7 is preferably hydrogen; A methylene or ethylene group or an oxygen atom; W is ethylene, vinylene or 1,2-propylene; Q1 is hydrogen or hydroxy; and Lv and their salts, their preparation, use and pharmaceutical compositions for treating conditions, in particular proliferative and immunological diseases, associated with nuclear hormone receptors. HE |