| abstract |
The present invention relates to compounds of the general formula: wherein Ar1 and Ar2 are substituted aryl or heteroaryl; X is oxygen, sulfur or cyanomino; Y is a single bond or an alkylene group; Cycloalkylene or heterocycloalkylene, optionally substituted with one or two double bonds and optionally up to four times in the present case; R 1 is optionally substituted aryl, heteroaryl, cycloalkyl, heterocycloalkyl, different substituted amino; R2 is a hydrogen atom or an alkyl group, and a pharmaceutically acceptable salt or solvate thereof, a pharmaceutical composition comprising them, and their preparation. The compounds of the invention are useful as agents for treating melanin concentrating hormone (MCH) and agonists of obesity, metabolic disorders, eating disorders such as hyperphagia and diabetes. HE |