| abstract |
The present invention relates to compounds of the general formula wherein R1 is optionally substituted phenyl; R2 is optionally substituted phenyl or heteroaryl; R3 is hydrogen or alkyl; R4 is ethyl, allyl or cyclopropyl; R 5 is hydrogen, halogen, hydroxy, nitro, -S (O) 2-alkyl, -S (O) 2NH 2, -S (O) 2N (alkyl) 2, cyano, alkyl, alkoxy. -, -C (O) NH 2, -C (O) NHalkyl, -C (O) N (alkyl) 2, -CO 2 H, -CO 2 alkyl, -NHC (O) alkyl, -NHS (O) 2 alkyl, -C ( O) alkyl, trifluoromethyl or trifluoromethoxy; R6 is alkyl; k, m and n are each independently 0, 1 or 2 and their pharmaceutically acceptable salts or solvates, their preparation and pharmaceutical compositions containing them. HE |