| abstract |
The present invention relates to compounds of the general formula wherein n = 0, 1, 2 or 3; A = C (R 1) - or N (= N -); R 1 and R 1a are each independently hydrogen, alkyl, halogen, cyano or trifluoromethyl: X is -C (O) -, -O-, -SO 0-2 or optionally substituted methylene, imino, arylene or heteroaryldyl; Y is -O-, -SO (0-2) or an optionally substituted arylene, heteroaryldyl or nitrogen-containing heterocycloalkyl group or a bond with certain provisions; Radically substituted aryl or heteroaryl; and R 2 is optionally substituted aryl, heteroaryl, arylalkyl or heteroarylalkyl; or R2-Y is a fused piperidinyl, substituted piperazinyl or substituted piperidinyl and their use in the preparation of pharmaceutical compositions for treating Parkinson's disease alone or in combination with other agents for the treatment of Parkinson's disease and the like. SHE |