http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-0401760-A2

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filingDate 2002-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d8709757a1204e071b92cee1af5e232
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f341fb856a2fd6bbaafee319024d4f8
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publicationDate 2004-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber HU-0401760-A2
titleOfInvention A stent, a process for its preparation and its use in the treatment of restenosis and / or thrombosis
abstract The present invention relates to stents comprising anticoagulant factor Xa and to a process for the preparation and use of a stent, in particular for the treatment and / or prevention of thrombosis and / or restenosis. The stent of the invention comprises one or more compounds of formula (I) wherein R1 is 2-thiophene substituted at the 5-position with a group selected from chloro, bromo, methyl or trifluoromethyl, R2 is DA-, wherein A is phenylene, D is a saturated 5- or 6-membered heterocycle attached via A to A, which contains a carbonyl group in the immediate vicinity of the attached nitrogen, and wherein a ring hydrocarbon moiety may be substituted with a heteroatom selected from sulfur, nitrogen and oxygen; wherein the group A as defined above is substituted in the meta position relative to its oxazolidinone attachment, optionally mono- or di- with a group selected from fluoro, chloro, nitro, amino, trifluoromethyl, methyl or cyano, R3, R4, R5, R6, R7 and R8 are hydrogen; and pharmaceutically acceptable salts, hydrates and / or mixtures thereof. SHE
priorityDate 2001-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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