| abstract |
The antibody of the invention interacts with human DR5 to produce agonist or antagonist activity on the receptor signaling pathway, including inhibition of cell proliferation and apoptosis. Nucleic acid sequences and amino acid sequences of anti-DR5 antibodies have been disclosed, and vector and cells containing and expressing such sequences have been generated. The present invention relates to methods and methods for treating antibodies, including apoptosis-related diseases, and treating defectively regulated cell proliferation. HE |