| abstract |
The present invention relates to a compound for use as an NPY Y5 receptor antagonist, a compound of the formula wherein R1 is alkyl, cycloalkyl or aryl; R2 is hydrogen or alkyl; or R1 and R2 taken together are alkylene; n 1 or 2; Xalkylene, alkenylene, arylene or cycloalkylene or a divalent heterocyclic group; Y is -OCONR7-, -CONR7-, -CSNR7-, -NR7CO- or -NR7CS- wherein R7 is hydrogen or alkyl; and Z, optionally substituted alkyl, alkenyl, amino, alkoxy, carbocyclyl, or heterocyclyl, or prodrug derivatives, salts or solvates thereof, contain pharmaceutical formulations, some of the novel compounds of formula (I) are pharmaceutical applications. HE |