http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-0302918-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0f4f8190960626ec922a1f03bcd4aba |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4468 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
| filingDate | 2001-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79eab9d6a53fadbcb3c67ed9bd17b41e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_783f44b56492b3450cb5c3c1c545eef4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9494cd2535565741f7a9941963184d33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0aa9564fb4f5277d616cf07b18c2c6c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1d233c38fcf5bcb6087c62665363a5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29fd5577435bb078ef5a1dd54839642b |
| publicationDate | 2003-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-0302918-A2 |
| titleOfInvention | Anti-microbial oxazolidinone derivatives and pharmaceutical compositions containing the compounds and a method for preparing the compounds |
| abstract | The present invention relates to novel substituted phenyloxazolidinone derivatives and to a process for their preparation. The novel compounds are represented by the following formula: The compounds of formula (I) and their pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs or metabolites, wherein T is a 5-7 membered heterocyclic ring, aryl, substituted aryl; which is attached to the C ring via a W group, the further substituents on the heterocyclic and azaryl rings are R, X is -CH-, -CH-S-, -CH-O- and nitrogen; Y and Z are independently hydrogen, C 1-16 alkyl, C 3-12 cycloalkyl, and C 0-3 bridging, and U and V are independently C 1-6 alkyl, F, Cl, Br, -C12 alkyl substituted with one or more F, Cl, Br, I is -CH2-, -CO, -CH2NH-, -NHCH2-, -CH2NHCH2-, -CH2N (R11) CH2-, -CH2 (R11) N-, -CH (R11) -, -S-, -CH2 (CO) -, -NH-, wherein R11 is optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, aryl, heteroaryl; R 1 is -NHC (= O) R 2, wherein R 2 is hydrogen, C 1-12 alkyl, C 3-12 cycloalkyl, C 1-6 alkoxy, C 1-6 alkyl selected from one or more of F, Cl, Br , I or -OH, and -N (R3, R4), -NR2C (= S) R3, -NR2C (= S) SR3, wherein R2 is as defined above, R3, R4 are independently hydrogen, C 1-12 alkyl, C 3-12 cycloalkyl, C 1-6 alkoxy, C 1-6 alkyl substituted with one or more F, Cl, Br, I or -OH groups. The compounds of the present invention exhibit significant antimicrobial activity, and thus the present invention also relates to pharmaceutical compositions containing these compounds. |
| priorityDate | 2000-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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