| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1394e66eb648f9bf0a1f5507fe25b67b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C205-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C205-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C205-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C205-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C221-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C225-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C221-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-147
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C225-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 |
| filingDate |
2002-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4907ee2d1ad8c4e62562bf5c06805da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_791b8eb46540ec87ded81845658bd3b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_579de79055b0e7016faf8e92571dd7f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4da8376d0e50a264e23e25f74dff3534 |
| publicationDate |
2003-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
HU-0302755-A2 |
| titleOfInvention |
A method for preparing camptothecin analog compounds |
| abstract |
The present invention relates to a process for the preparation of 2'-amino-5'-hydroxypropiophenone of formula (e) which can be used for the synthesis of camptothecin analogues by converting a compound of formula (a) to a compound of formula (b), a compound of formula (b) (c) a compound of formula (c) is converted to a compound of formula (d) and a compound of formula (d) is converted to a 2'-amino-5'-hydroxypropiophenone of formula (e) - wherein R can be cleaved by catalytic reduction védőcsoportotjelent. The invention further provides a process for the preparation of a tricyclic ketone of formula (h) for the synthesis of camptothecin analogs by an improved method. Camptothecin analogs can be prepared with good efficiency by reacting the compounds of formulas (e) and (h) and subsequently converting them as necessary. SHE |
| priorityDate |
2001-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |