| abstract |
SUMMARY OF THE INVENTION The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein: R 1 represents a halogen substituted benzofuranyl group or a halogen substituted styryl group; R2 is substituted hydroxy, substituted mercapto or substituted sulfonyl; and X is a group of formula (a), (b) or (c). The compounds of formula (I) and their pharmaceutically acceptable salts according to the present invention have potent inhibitory effects on nitric oxide (NO) production and are therefore useful in the prevention and / or treatment of NO-mediated diseases in animals and humans. HE |