http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-0302496-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05ff905fdc49089f5f25746eaeb40190 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0459 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0446 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 |
| filingDate | 2000-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_473e71643bae988676e6f19b82e324b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bba47f4510cbc19f828fc3cdb7ac704 |
| publicationDate | 2003-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-0302496-A2 |
| titleOfInvention | The use of Nempeptide bombesin receptor antagonists for the treatment of anxiety and panic disorder |
| abstract | SUMMARY OF THE INVENTION The present invention relates to compounds of formula I wherein j is 0 or 1; k is 0 or 1; l is 0, 1, 2 or 3; m is 0 or 1; n is 0, 1 or 2; Ar is phenyl, pyridyl or pyrimidyl, each of which may be unsubstituted or substituted with 1 to 3 substituents selected from the group consisting of halogen, alkyl, alkoxy, acetyl, nitro, amino, -CH 2 NR 10 R 11, cyano, trifluoromethyl; , -NHCONH2 or -CO2R12; R 1 is hydrogen or straight, branched or cyclic C 1 -C 7 alkyl; R 5 is hydrogen or R 5 may form a C 3 -C 7 ring with R 1; R2 is hydrogen or straight, branched or cyclic alkyl having 1 to 8 carbon atoms, which may contain 1 to 2 oxygen or nitrogen atoms; R9 is hydrogen or R9 may be optionally substituted with R2 to form a C3-C7 ring which may contain oxygen or nitrogen; or R 2 and R 9 together form a carbonyl group; Ar1 is a group defined by Ar or pyridyl N-oxide, indolyl, imidazolyl or pyridyl; R4, R5, R6 and R7 are independently hydrogen or lower alkyl, R4 may also form a covalent bond of 2 to 3 atoms with R5 which may include oxygen or nitrogen; R3 is as defined for Ar, hydrogen, hydroxy, -NMe2, N-methylpyrrolyl, imidazolyl, N-methylimidazolyl, tetrazolyl, N-methyltetrazolyl, thiazolyl, -CONR13R14, alkoxy , a) to e) wherein p is 0, 1 or 2 and Ar 2 is phenyl or pyridyl; use of a C 1 -C 4 alkyl compound or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for the treatment, prevention or diagnosis of any of the following disorders: anxiety and panic disorder, social phobia, hypertension of the small artery, gastrointestinal pulmonary gyulladásosfá pain, nerve pain, cancer-related pain, post-operative pain, tricuspid nerve pain, acute herpes pain, and post-herpes pain. HE |
| priorityDate | 2000-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 175.