| abstract |
FIELD OF THE INVENTION The present invention provides a novel substituted benzoic acid derivative represented by the general formula (I): wherein R 1 is a compound of formula (II): (wherein R 3, R 4 and R 5 are independently hydrogen, C 1-6 alkyl or C 1-6); alkoxy, and R 9 and R 10 are independently hydrogen, C 1-6 alkyl or 2-11 carbon atoms; R2 is hydrogen, C1-6alkyl, which may be substituted, C6-C12 aryl, which may be substituted, C4-C11 heteroaryl, which may be substituted, C7-C14 aralkyl, which may be substituted, C5-C13 heteroarylalkyl which may be substituted or C2-C11 acyl; and X is a carboxyl group which may be esterified or amidated and refers to NF-kB inhibitory compositions containing the compound. HE |