abstract |
According to the invention there are provided compounds of formula (I) and salts thereof wherein Py is 2-, 3- or 4-pyridyl and R is a substituted or unsubstituted phenyl group or a substituted or unsubstituted aromatic heterocyclic group. The invention furthermore relates to agents which have an inhibitory effect on steroid 17α-hydroxylase and / or steroid C17-20 lyase, and to pharmaceutical compositions containing the benzofuran derivatives of the above formula (I) or their salts. The compounds according to the invention can be used as prophylactic and / or therapeutic agents in the treatment of androgen- and estrogen-dependent diseases, such as aprotic cancer, prostate hypertrophy, androgenic syndrome, baldness, breast cancer, uterine cancer, endometriosis and ovarian cancer. SHE |