http://rdf.ncbi.nlm.nih.gov/pubchem/patent/HU-0301301-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D267-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D267-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
| filingDate | 2001-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_988dadb47314ba4a045dd28851b0be3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6055953a15aa30f05317c4735c73d6e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c5c7dc237c167b4b2026a8af2326763 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0cdd308b08420de1854b61513856544 |
| publicationDate | 2003-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | HU-0301301-A2 |
| titleOfInvention | Their use as benzoxazepinone derivatives and squalene synthase inhibitors and pharmaceutical compositions containing them |
| abstract | The present invention relates to novel benzoxazepinone derivatives and pharmaceutical compositions containing them for the prevention and / or treatment of hyperlipidemia and to the reduction of cholesterol and triglyceride levels. In the compound of formula (I), R1 is 1-carboxyethyl, carboxyalkyl, alkylsulfonyl, carboxycycloalkylalkyl, or a group -X1-X2-Ar-X3-X4-COOH. , (wherein X1 and X4 are a bond or an optionally substituted C1-4 alkylene group, X2 and X3 are a bond, -O- or -S-, and Ar is an optionally substituted divalent aromatic group, with the proviso that when X1 is a bond, then X2 is a bond, and when X4 is a bond, X3 is a bond), R2 is a C3-6 alkyl group optionally substituted with an alkanoyloxy group and / or a hydroxyl group, R3 is a lower alkyl group, and W is a halogen atom, provided that when R 1 is optionally substituted 1-carboxyethyl, optionally substituted C 3-6 straight alkyl, 4-carboxycyclohexylmethyl or 4-carboxy. methylphenyl, then R2 is C3-6 alkyl substituted with alkanoyloxy and / or hydroxyl, or a salt of the compound. SHE |
| priorityDate | 2000-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1281.