| abstract |
The present invention relates to compounds of the general formula wherein X is CH (= CH-) or N; Y is hydrogen or halo, trihaloalkyl, alkyl, alkenyl, cycloalkyl, mercapto, alkylthio or cyano; R is alkyl, trifluoromethyl, cycloalkyl, heterocycloalkyl, heterocycloalkylalkyl, heteroarylalkyl, adamantyl, and optionally substituted phenyl, phenoxyalkyl, (phenylthio) alkyl, pyridyl -, thienyl, thiazolyl, pyrazinyl or 1,2,5,6-tetrahydropyridinyl or a group of the general formula wherein R10 and R11 are hydrogen, alkyl or cycloalkyl together with their salts, solvates or N-oxides, pharmaceutical compositions containing them, and their application. SHE |