| abstract |
The present invention relates to lung surface active compositions which are capable of forming a dynamically swelling phase dispersed in a medium containing haelectrolyte. The dynamic swelling process can be traced by polarized microscopy and creates a double breaker network or tubes at the air / liquid interface. The effect of the dynamic swelling process is that the lung surface active substance is spread over a larger surface than when it is in a non-dynamic swelling phase. During the spreading period, it occurs after the lung surface active agent is dispersed, for example in a physiological electrolyte solution. into lungs or other organs, or otherwise into body parts that are difficult to access. The lung surface active composition according to the invention comprises a lung surface active agent which, when powdered or in the form of granules in the form of vandalization in 0.9% sodium chloride, at a concentration of 10%, at ambient temperature, is capable of forming a double crushing network or tubes during swelling. air-liquid-solid at interface approx. Within 0.5-120 minutes as observed by polarized microscopy. HE |