abstract |
The present invention relates to an important intermediate in the preparation of 5- (4-chlorobenzyl) -2,2-dimethylcyclopentanone, the synthesis of metconazole and other agricultural and horticultural antifungal agents, in good yield. 3-Methyl-2-oxo-cyclopentanecarboxylic acid methyl or ethyl ester, sodium hydride and methyl halide, followed by 1- (4-chlorobenzyl) -3,3-dimethyl-2-oxo-cyclopentanecarboxylic acid -methyl or ethyl ester hydrolysis. HE |