| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6572ff5df928fd17340eb2a8cb6d8502 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 |
| filingDate |
2003-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fdcd08c184de339633ae9c65f211c07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64c1e44d2a4aabb2a4f1d654d460e607
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7240115990564141d9dc6f0f1ca9bb01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ce1bef7f9e4d74a435ac174c38fdc9a |
| publicationDate |
2003-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
HU-0300231-A2 |
| titleOfInvention |
Process for the preparation of high purity perindopril and intermediates used in the process, pharmaceutical compositions containing the compound and their use |
| abstract |
This invention relates to 1- (2 (S) - [1 (S) - (ethoxycarbonyl) butylamino] propionyl) - (3aS, 7aS) octahydroindole-2 (S) -carboxylic acid of formula (I) and its tertiary compound of formula (I '). refers to its butylamine salt, which is free of impurities derived from dicyclohexylcarbodiimide. The invention also relates to a process for the preparation of the compounds as well as to novel intermediates of formula (III) in which R is lower alkyl or aryl (lower alkyl). The compound of formula (I), perindopril, is a known ACE inhibitor. SHE |
| priorityDate |
2002-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |