abstract |
The present invention relates to a process for the preparation of a well-known antidepressant citalopram, i. E. In its invention, a compound of formula (III) wherein X is a cyano group or a cyano-convertible group is converted and, if X is cyano-displaced, is converted to a cyano group, then the citalopram base or a pharmaceutically acceptable acid addition salt thereof is isolated. HE |