| abstract |
The present invention relates to novel processes for the delivery of a therapeutic agentococal targeting agent, wherein the desired cell type targeting caspase conjugate is administered, followed by pro-drug delivery, which, in the presence of caspase, undergoes local action of the active substance. The present invention also relates to caspase-containing delivery agents and pro-drugs containing caspase-cleavable pro-drug molecules. The present invention also relates to caspase conjugates and pro-drug formulations of the present invention, as well as to methods of treating the invention with the use of caspase conjugates and drugs. HE |