| abstract |
The present invention relates to uracil-substituted sulfamoyl carboxamides of the general formula wherein A is oxygen or sulfur; X 1 is hydrogen, halogen, C 1-4 alkyl; X2 is hydrogen, cyano, CS-NH2, halogen, C1-C4 alkyl, halogenated C1-C4 alkyl; X 3 is hydrogen, cyano, C 1 -C 6 alkyl, C 1 -C 6 alkoxyalkyl, C 3 -C 7 cycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, or optionally substituted benzyl; R1, R2 are hydrogen, optionally substituted hydroxy, C1-C10 alkyl, C2-C10 alkenyl, C3-C10 alkynyl, C3-C7 cycloalkyl, phenyl, benzyl or C5-C7 cycloalkenyl; or R 1 and R 2 together with the atom to which they are attached form a 3- to 7-membered heterocyclic ring; Q is a 5-6 membered heterocyclic group containing 1-3 nitrogen atoms with different substituents, and salts thereof, and their uses. SHE |