abstract |
The present invention relates to compounds, pharmaceutical compositions and methods for modifying processes mediated by androgen and progesterone receptors. The non-steroidal compounds of the invention are high affinity, highly specific agonists, partial agonists (i.e., partial and / or tissue-specific activators) or antagonists of the androgen and progesterone receptors. The invention also relates to processes for the preparation of such compounds and pharmaceutical compositions and to critical intermediates for their synthesis. SHE |