| abstract |
The present invention relates to substituted glutarimide compounds of formula (I) wherein X is (CH 2) n - (CR 8 R 9) p -Z - (CR 8 R 9) m; Z is sulfur, oxygen, SO, SO2, NR8, optionally in the form of N-oxide, or CR8R9; m and p are 0 or 1; n is 0, 1, 2 or 3; and at least one of m, n and p has a value other than 0. The invention further relates to the preparation of compounds of the formula I and their use as a pharmaceutical active ingredient, in particular as an immunomodulator and as an inhibitor of antigopathic and / or haematological / oncological diseases. SHE |