| abstract |
The present invention relates to compounds of the general formula wherein R1 is optionally substituted alkyl; R 2 is hydrogen, halogen, C 1-6 alkyl; R 3 is hydrogen, (C 1 -C 6) -alkyl, or together with R 2 = O is one or more hydroxy, cyano, halo, nitro, (C 1 -C 6) -alkyl, optionally substituted; R41-R46 are each independently hydrogen or alkyl of 1 to 6 carbon atoms; Direct bond or other linking group; Linking group B; G = CH or N - and pharmaceutically acceptable derivatives thereof and pharmaceutical compositions containing them for use in the treatment of arrhythmias. The invention also relates to a process for the preparation of the compounds. SHE |