| abstract |
kPage = N; BrkToNext = N; > (57) The present invention relates to a novel process for the preparation of quinoline compounds of formula I or pharmaceutically acceptable salts thereof, wherein R is hydrogen or methyl; R1 represents a bromine or chlorine atom or a nitro group; and R2, R3 and R4 are independently hydrogen or halogen, nitro or trifluoromethyl, with the proviso that R2, R3 and R4 are not simultaneously hydrogen; an important intermediate of the process is a compound of formula VI, wherein the substituents have the meanings given above, which are converted to the compound of formula I by photochemical irradiation. SHE |