abstract |
SUMMARY OF THE INVENTION The present invention relates to delayed-release complexes, complexes (I) comprising a somatostatin derivative of formula (A) or a pharmaceutically acceptable salt thereof, and a poly (L) lactic acid glycolic acid tartaric acid (P (L) LGT), wherein The amino group of the compound of formula (A) is linked by ionic bond to the LGTcarboxy group of P (L). The compound of formula (A) is released according to the complex zero profile of formula (I). The present invention further relates to a method for the production of a delayed release complex as described above. The present invention also relates to the preparation of the above-mentioned delay release complex and pharmaceutically acceptable carrier compositions, and also to the preparation of microparticles and complexes of Complex (I). HE |