| abstract |
Benzazepine-N-acetic acid derivatives, their salts and their biolabile esters containing an oxo group at the a-position relative to the nitrogen atom and substituted at the 3-position with a 1-carboxyalkylcyclopentylcarbonylamino group and / or treatment. In particular, the present invention relates to the prevention and / or treatment of cardiac damage, in particular myocardium, due to cytostatic chemotherapy. Fentibenzazepine-N-acetic acid derivatives can also be used as adjuvant therapies in the use of therapeutics that use drugs with oxidative-toxic side effects. The preparation of pharmaceutical compositions for the above prophylaxis and / or treatment and adjuvant treatment is also subject to the patent. SHE |